Biliary Enhancement of Gd-BOPTA (MultiHance®) and Gd-EOB-DTPA (Primovist®) - a Study in Healthy Volunteers
نویسندگان
چکیده
N. Dahlström, T. B. Brismar, A. Persson, N. Albiin, Ö. Smedby Center for Medical Image Science and Visualization (CMIV), Linköping University Hospital, Linköping, Sweden, Department of Radiology, Hudiksvall Hospital, Hudiksvall, Sweden, Department of Radiology, Karolinska University Hospital Huddinge, Stockholm, Sweden Introduction: The gallbladder and in particular the bile ducts are readily depicted by heavily T2-weighted MRC(P) acquisitions. Contrast media giving intraluminal enhancement in the biliary system can, in addition to displaying its morphology, also provide functional dynamic information of the hepatobiliary system. There are two contrast agents based on gadolinium which may be used, Gd-BOPTA (Multihance®) and Gd-EOB-DTPA (Primovist®). They differ in hepatocellular enhancement properties as well as in the degree of biliary elimination (5% for Gd-BOPTA and 50% for GdEOB-DTPA). This study aimed to investigate the dynamics of bile duct enhancement relative to that of liver parenchyma for both these contrast agents.
منابع مشابه
Contrast-enhanced magnetic resonance cholangiography with Gd-BOPTA and Gd-EOB-DTPA in healthy subjects.
PURPOSE To evaluate the biliary enhancement dynamics of the two gadolinium chelates Gd-BOPTA (MultiHance) and Gd-EOB-DTPA (Primovist) in normal healthy subjects. MATERIAL AND METHODS Ten healthy volunteers were evaluated with both agents by magnetic resonance (MR) imaging at 1.5T using a breath-hold gradient-echo T1-weighted VIBE sequence. The relative signal intensity (SI) differences betwee...
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